ChemInform Abstract: Mild, Stereoselective, and Highly Efficient Synthesis of N‐Acylhydrazones Mediated by CeCl₃·7H₂O in a Broad Range of Solvents.

Abstract

The catalyst is active in various protic and aprotic solvents including water, but EtOH is the medium of choice.

Streptindole and Its Derivatives as Novel Antiviral and Anti-Phytopathogenic Fungus Agents

“…The analysis of the 1 H NMR spectra revealed that compounds 15a−15h exist as Z/E isomers, and the proportion of isomers can be determined according to the literature methods. 28,29 Phytotoxic Activity. The phytotoxic-activity tests (according to the criterion of safety evaluation of pesticide to crops: NYT 1965.1-2010) revealed that compounds 3a−3c, 4, 5, 8, 10, 11, 12a−12d, 13a−13l, 14, and 15a−15h were safe for testing on plants at 500 μg/mL.…”

“…1 H NMR (400 MHz, CDCl 3 ): δ 8.00 (s, 2H, indole-NH), 7.64 (d, J = 8.0 Hz, 2H, Ar−H), 7.36 (t, J = 8.4 Hz, 4H, Ar−H), 7 29. (d, J = 7.0 Hz, 1H, Ar−H), 7.18−7.24 (m, 3H, Ar−H), 6.99−7.08 (m, 5H, Ar−H), 6.63 (d, J = 7.8 Hz, 1H, CH 2 −NH), 6.17 (s, 1H, CH 2 NHCS−NH), 4.97 (t, J = 7.1 Hz, 1H, Ar 2 −CH), 4.43 (t, J = 5.4 Hz, 2H, CH 2 ); 13 C NMR (100 MHz, DMSO-d 6 ): δ 180.4, 139.6, 137.0, 130.4, 129.0, 127.2, 124.4, 123.2, 123.0, 121.4, 119.5, 118.7, 116.5, 111.9, 48.9, 33.5.…”