ChemInform Abstract: Lipase‐Catalyzed Kinetic Resolution of Z‐Configured Homoallylic Alcohols.

Abstract

biochemical syntheses, microbiological syntheses biochemical syntheses, microbiological syntheses O 0035 -042Lipase-Catalyzed Kinetic Resolution of Z-Configured Homoallylic Alcohols.-Successful resolution is achieved in the case of alcohols (IIIa) and (IIIb), whereas the analogues with R: -iPr or -tBu do not react. Excellent results for alcohol and acetate product concerning the e.e. value are obtained with (IIIa); the phenyl derivative (IIIb) affords either good e.e. for the alcohol or the acetate. The saturated analogue (VI) is resolved with good e.e. for both products. -(ADAM, WALDEMAR; SAHA-MOELLER, CHANTU R.; SCHMID, KATHARINA S.; Tetrahedron: Asymmetry 10 (1999) 2, 315-322; Inst. Org. Chem., Julius-Maximilians-Univ.,