ChemInform Abstract: Knoevenagel Adducts as Trimethylenemethane Dipole Surrogates.

Abstract

Knoevenagel Adducts as Trimethylenemethane Dipole Surrogates. -A novel strategy is disclosed for the difunctionalization of Knoevenagel adducts (I) and (VIII). The process involves Pd(0)-catalyzed allylation with allyl-tert-butyl carbonates and a second Pd-catalyzed coupling with O-or C-nucleophiles. -(VERTESALJAI, P.; NAVARATNE, P. V.; GRENNING*, A. J.; Angew. Chem., Int. Ed. 55 (2016) 1, 317-320, http://dx.