ChemInform Abstract: Influence of Catalyst Structure and Reaction Conditions on anti‐versus syn‐Aminopalladation Pathways in Pd‐Catalyzed Alkene Carboamination Reactions of N‐Allylsulfamides.

Abstract

Cyclic sulfamides are obtained by Pd‐catalyzed coupling of N‐allylsulfamides with aryl and alkenyl triflates.

Efficient and environmentally-friendly access to 4,5-unsaturated sulfonamides through ligand-free copper-BF3-catalyzed three-component alkene carbo-sulfonamidation

“…36 For example, Wolfe and co-workers used alkene-tethered sulfonamides for carbo-sulfonamidation reaction with alkyl halide as a carbon donor, resulting in cyclic sulfonamide ring formation (Scheme 1a). [37][38][39] These two-component carbo-sulfonamidation reactions were carried out in the presence of a palladium catalyst and a stoichiometric quantity of an alkoxy base. Dang et al, used alkene-tethered aromatic sulfonamides to obtain cyclic sulfonamides in the presence of large quantities of Cu(OAc) 2 , KHCO 3 as a base, and MnO 2 as an oxidant.…”