ChemInform Abstract: Indirect C—H Azidation of Heterocycles via Copper‐Catalyzed Regioselective Fragmentation of Unsymmetrical λ³‐Iodanes.

Abstract

Indirect C-H Azidation of Heterocycles via Copper-Catalyzed RegioselectiveFragmentation of Unsymmetrical λ 3 -Iodanes. -A convenient approach to the synthesis of heteroaryl-substituted azides via C-H activation is followed by direct 1,3-dipolar Cu-catalyzed cycloaddition with terminal alkynes or by direct Cu-catalyzed reductive fragmentation to amino compounds. A variety of heterocyclic systems bearing triazole moieties is available. -(LUBRIKS, D.; SOKOLOVS, I.; SUNA*, E.; J. Am. Chem. Soc. 134 (2012) 37, 15436-15442, http://dx.doi.org/10.1021/ja305574k ; Latv. Inst. Org. Synth., Riga 1006, Latvia; Eng.) -Mais 09-121