ChemInform Abstract: IBiox[(‐)‐menthyl]: A Sterically Demanding Chiral NHC Ligand.

Abstract

Indole derivatives R 0140IBiox[(-)-menthyl]: A Sterically Demanding Chiral NHC Ligand. -An exceedingly sterically demanding, rigid chiral ligand, is prepared and applied in the asymmetric α-arylation of amides. The ability to use aryl chloride substrates reveals its unique reactivity. -(WUERTZ, S.; LOHRE, C.; FROEHLICH, R.; BERGANDER, K.; GLORIUS*, F.; J. Am. Chem. Soc. 131 (2009) 24, 8344-8345; Org.-Chem. Inst.,