ChemInform Abstract: Highly Enantioselective [4 + 2] Annulation via Organocatalytic Mannich‐Reductive Cyclization: One‐Pot Synthesis of Functionalized Piperidines.

Abstract

Highly Enantioselective [4 + 2] Annulation via Organocatalytic Mannich-Reductive Cyclization: One-Pot Synthesis of Functionalized Piperidines. -The practicability of the described method is illustrated by gram-scale application and through the synthesis of a functionalized (-)-anabasine derivative (IV*). -(KUMAR*, I.; RAMARAJU, P.; MIR, N. A.; SINGH, D.; GUPTA, V. K.; RAJNIKANT; Chem. Commun. (Cambridge) 49 (2013) 50, 5645-5647, http://dx.doi.org/10.1039/c3cc42431f ; Dep. Chem., Birla Inst. Technol. Sci., Pilani 333 031, India; Eng.) -M. Duhs 42-139