ChemInform Abstract: Highly Efficient and Practical Syntheses of Lavendamycin Methyl Ester and Related Novel Quinolindiones.

Abstract

Highly Efficient and Practical Syntheses of Lavendamycin MethylEster and Related Novel Quinolindiones.-An efficient method for the preparation of multigram amounts of the potent antitumor agent lavendamycin methyl ester (VI) is reported. The procedure is based on a novel route to the dione intermediate (V). -(BEHFOROUZ, M.; HADDAD, J.; CAI, W.; ARNOLD, M. B.; MOHAMMADI, F.; SOUSA, A. C.; HORN, M. A.;