ChemInform Abstract: Highly Diastereoselective Synthesis of (‐)‐Petasinecine via Ireland‐ Claisen‐Type Rearrangement.

Abstract

Highly Diastereoselective Synthesis of (-)-Petasinecine via Ireland-Claisen-Type Rearrangement.-The L-proline derived allyl ester (I) undergoes a Ireland-Claisen-type rearrangement process to give the bicyclic compound (II) as a single stereoisomer. This is further transformed into the desired base (III). -(MULZER, J.; SHANYOOR, M.; Tetrahedron Lett. 34