ChemInform Abstract: Gold and Palladium Combined for Cross‐Coupling.

Abstract

Gold and Palladium Combined for Cross-Coupling. -Organogold(I) complexes undergo cross-coupling with aryl iodides (and bromides) in the presence of catalytic amounts of a palladium complex. The gold furanone complexes (I) exhibit an unprecedented thermal stability which allows reactions at elevated temperature. The gold can be recovered in nearly quantitative yield as iodo(triphenylphosphine)gold complex.-(HASHMI*, A. S. K.; LOTHSCHUETZ, C.; DOEPP, R.; RUDOLPH, M.; RAMAMURTHI, T. D.; ROMINGER, F.; Angew.

Rapid synthesis of arylgold compounds using dielectric heating

“…6b Furthermore, the ability of arylgold compounds to readily transfer the aryl fragment to another metal center has given rise to the use of arylgold complexes as transmetallating agents in palladium catalyzed cross-coupling reactions. 7,8 These organometallic complexes are commonly prepared through the treatment of chlorogold precursors with Grignard or organolithium reagents 9,10 or tetraphenylborate. 11 While often successful, this methodology suffers from significant functional group intolerance.…”