ChemInform Abstract: Glycosylation Employing Unprotected Carbohydrate Acceptor Components.

Synthesis of a 1,2-cis-indoxyl galactoside as a chromogenic glycosidase substrate

“…2A-i). 4 These basic conditions are required to generate the enolate form from the cyclic ketone version of the free indoxyl, which exists in ketoenol equilibrium in the reaction medium and almost none of the corresponding enol forms in nonpolar solvents. 5 Unfortunately, these conditions result in low yields, in addition to the formation of various side products, including indigogenic compounds and acetyl migration and/or elimination products generated from the donor.…”