ChemInform Abstract: Functionalization of Some Benzylthioarylboronic Acids by Benzylic Lithiation of Their N‐Butyldiethanolamine Esters or Lithium(triisopropoxy)borates.
Abstract:Esters or Lithium(triisopropoxy)borates. -New arylboronic acids substituted in the benzylic position are synthesized by reaction of protected benzylthioarylboronic acids with various electrophiles. Benzylic lithiation occurs selectively using LDA. The method is also applicable to brominated aryl-benzyl sulfides which are initially transformed into triisopropoxyborates using tert-butyllithium for the first lithiation followed by second lithiation with LDA. Finally, lithiated intermediates are converted to the r… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.