ChemInform Abstract: Fluoroanalogues of DDT: Superacidic BF₃—H₂O Catalyzed Facile Synthesis of 1,1,1‐Trifluoro‐2,2‐diarylethanes and 1,1‐Difluoro‐2,2‐diarylethanes.

Abstract

diarylethanes. -The reaction substrate (I) with various arenes is mediated by BF3·Et2O or TFA with comparable yields. In the latter case, the reaction time is reduced. Nitrobenzene affords only the intermediate carbinol (V). Monosubstituted arenes mostly afford inseparable mixtures. The reaction with hemiacetal (VI) proceeds under mild conditions and with high regioselectivity. -(PRAKASH*, G. K. S.; PAKNIA, F.; MATHEW, T.; MLOSTON, G.; JOSCHEK, J. P.; OLAH, G. A.; Org. Lett. 13 (2011) 15, 4128-4131, http://dx.