ChemInform Abstract: First Synthesis of Bi‐ and Tricyclic α,β‐Unsaturated δ‐Oxacaprolactams from Cyclic Imines via Ring‐Closing Metathesis.

Abstract

First Synthesis of Bi-and Tricyclic α,β-Unsaturated δ-Oxacaprolactams from Cyclic Imines via Ring-Closing Metathesis. -The procedure is based on an acyl chloride addition in the first step, followed by ring-closing metathesis. The lactams are potentially bioactive due to their similarity to known and examined lactams. -(WATZKE, M.; SCHULZ, K.; JOHANNES, K.; ULLRICH, P.; MARTENS*, J.; Eur.