ChemInform Abstract: Facile Access to Imidazole Derivatives: Carboxylic Acids and δ‐Lactones.

Abstract

Facile Access to Imidazole Derivatives: Carboxylic Acids and -Lactones. -Nucleophilic addition of acetals (III) to doubly activated imidazole derivatives affords carboxylic acids. Subsequent NBS mediated regioselective ring closing provides access to new bicyclic -lactones (IX). -(RIVERA-HERNANDEZ, A.; LOPEZ-JIMENO, I. S.; CARMONA-REYES, G. A.; ALFREDO-TOSCANO, R.; PENIERES-CARRILLO, J. G.; ALVAREZ-TOLEDANO*, C.; Tetrahedron Lett. 56 (2015) 33, 4829-4832, http://dx.