ChemInform Abstract: ESTERIFICATION OF PYRIDINECARBOXYLIC ACIDS IN THE PRESENCE OF CATION EXCHANGERS

Abstract

Beim Erhitzen der Dipicolinsäure (I) mit den Alkoholen (II) in Gegenwart des Kationenaustauschers KU‐2 erhält man die Diester (III) in Ausbeuten bis zu 99%.

6-Acetyl-2-(N-methylamido)pyridine

“…Adjacent molecules are linked by a weak N-HÁ Á ÁO hydrogen bond (Table 1) into a helical chain. Experimental 2,6-Pyridinedicarboxylic acid was converted to the diethyl ester (Levkoeva et al, 1976); the diethyl ester was dissolved in freshly distilled ethyl acetate and then treated with sodium ethoxide followed by hydrolysis with hydrochloric acid to yield ethyl 6-acetyl-2-pyridinecarboxylate (Sun et al, 2004). Ethyl 6-acetyl-2-pyridinecarboxylate (0.078 g, 0.4 mmol) and methylamine (0.114 g, 1.04 mmol) were placed in a 25-ml flask; the mixture was subjected to radiation in a 800 W microwave oven for 10 minutes on a mediumhigh setting (Yang et al, 2002).…”