ChemInform Abstract: Enzymes in Organic Synthesis. Part 2. Prostaglandins and Prostaglandin Intermediates. Part 23. Synthesis of Enantiomerically Pure Prostaglandin Intermediates by Enzymatic Hydrolysis of (1SR,5RS,6RS,7RS)‐7‐Acetoxy‐6‐acetoxymethyl‐2‐oxabicyclo(3.3.0)octan‐3‐one.

Abstract

Enzymatic hydrolysis of the title compound (I) leads to a mixture of enantiomeric diols, monoacetates and diacetates which are separated chromatographically.