ChemInform Abstract: Enantioselective Cu(II)‐Catalyzed Henry Reactions with Chiral Cyclohexane‐Based Amidophosphine Ligands.

Regioselective and Enantioselective Cu(II)-Catalyzed 1,4-Conjugate Addition of Diethylzinc Reagent to Nitrodienes

“…According to our recently established approach for developing novel amidophosphine ligands derived from chiral compound L1 and its enantiomer, 13 we designed a new series of amidophosphine ligands for copper-catalyzed 1,4-conjugate addition of dialkylzinc reagents to conjugated nitrodiene compounds (Figure 1). The combination of copper(II) and amidophosphine L3 was found to be an efficient catalytic system for this reaction.…”