ChemInform Abstract: Enantioselective Catalytic Carbonyl—Ene Cyclization Reactions.

Abstract

Enantioselective syntheses O 0031Enantioselective Catalytic Carbonyl-Ene Cyclization Reactions. -Intramolecular ene reactions of a variety of alkenyl aldehydes are catalyzed by the chiral Schiff base Cr(III) complex DCR to give highly functionalized heterocyclic and carbocyclic products with up to three contiguous stereocenters in high diastereo-and enantioselectivities. Desymmetrizations of alkenyl dialdehydes and bis (alkenyl) aldehydes are also accomplished under these conditions. -(GRACHAN, M. L.; TUDGE, M. T.; JACOBSEN, E. N.; Angew.