ChemInform Abstract: Diazinium Salts with Dihydroxyacetophenone Skeleton: Syntheses and Antimicrobial Activity.

Abstract

Pyridazine derivatives R 0500Diazinium Salts with Dihydroxyacetophenone Skeleton: Syntheses and Antimicrobial Activity. -Cycloimmonium salts [(III) and (V)] are synthesized starting from chloroacetophenone (I) using microwave and ultrasound irradiation. All compounds have an excellent antibacterial activity, and most of them a good antifungal activity. -(BALAN, A. M.; FLOREA, O.; MOLDOVEANU, C.; ZBANCIOC, G.; IUREA, D.; MANGALAGIU*, I. I.; Eur. J. Med. Chem. 44 (2009) 5, 2275-2279; Org. Biochem. Dep., Al. I. Cuza Univ., RO-700506 Iasi, Rom.; Eng.) -R. Langenstrassen 34-156