ChemInform Abstract: Design, Synthesis and Stability of N‐Acyloxymethyl‐ and N‐Aminocarbonyloxymethyl‐2‐azetidinones as Human Leukocyte Elastase Inhibitors.
Abstract:Design, Synthesis and Stability of N-Acyloxymethyl-and N-Aminocarbonyloxymethyl-2-azetidinones as Human Leukocyte Elastase Inhibitors. -The title compounds (VIII) and (X) are timedependent irreversible inhibitors of HLE. The most potent compounds are (Xb), (Xc), and (VIIIb) (no yields given). -(CLEMENTE, A.; DOMINGOS, A.; GRANCHO, A. P.; ILEY, J.; MOREIRA, R.; NERES, J.; PALMA, N.; SANTANA, A. B.; VALENTE, E.; Bioorg. Med.
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