ChemInform Abstract: DARST. VON ISOXAZOLEN UND ISOXAZOLINEN

Abstract

Die Bromierung der Chalkone (I) in essigsaurer Lösung führt zu den Chalkondibromiden (II) (70‐80% Ausbeute).

New Bis(chalcones) and Their Transformation into Bis(pyrazoline) and Bis(pyrazole) Derivatives

“…Our recent studies indicate, however, that these pyrazoles can be obtained in good overall yields from the reaction of hydrazine hydrate with chromones 18−19. There are, however, reports indicating that the treatment of 2‐hydroxychalcones or 2‐hydroxychalcone dibromides with phenylhydrazine in an alkaline medium affords pyrazoline derivatives 20. Here we report the synthesis of 3‐aryl‐5‐[3‐ and 4‐(3‐aryl‐2‐pyrazolin‐5‐yl)phenyl]‐2‐pyrazolines 4a − d and 3‐aryl‐5‐[3‐ and 4‐(3‐arylpyrazol‐5‐yl)phenyl]pyrazoles 5a − f from bis(chalcones) 1a − f and bis(chalcone) tetrabromo derivatives 3a − f 21…”

Synthesis and antiproliferative activity of some diaryldiazepines and diarylpyrimidines

“…The 1,3-diketones required for the work were obtained from the esters, by the base-catalyzed Baker-Venkataraman transformation [16]. Condensation of 2-hydroxyacetophenones with various substituted benzoic acids in dry pyridine and POCl 3 furnished the esters (1a -k).…”

Synthesis and Characterization of New 3,5-Dinaphthyl Substituted 2-Pyrazolines and Study of Their Antimicrobial Activity

“…have reported the formation of 1-phenyl-5-(2-hydroxy-4-methoxyphenyl)-3-methylpyrazoline from 2-hydroxy-4-methyl ketone on treatment with phenyl hydrazine [ 20 ]. Borkhade and Marathey have synthesized 3,5-diaryl-1-phenylpyrazoline by the action of phenyl hydrazine hydrochloride on 2′-hydroxy chalcones and flavanones in pyridine [ 22 ].…”