ChemInform Abstract: Convenient and Useful Esterification of Bulky Tertiary Alcohols Using Strontium Compounds.

Abstract

The reaction of various esters with metallic Sr and alkyl iodides followed by adding acid chlorides or anhydrides affords the corresponding bulky tertiary alcohol esters in good yields.

Beyond Amide Bond Formation: TCFH as a Reagent for Esterification

“…This includes a range of phenols such as electron-deficient phenol 4a or hindered phenol 4b . Aliphatic alcohols like 1-phenylethanol 4c , menthol 4d , isoborneol 4e , or 2-phenyl isopropanol 4f represent hindered unreactive substrates. To ensure an informed selection of the test alcohol, we investigated the kinetic reaction profiles of alcohols 4a – 4f in reaction with 2a under the optimal conditions for TCFH-NMI amidations using in situ IR.…”