ChemInform Abstract: CONCERNING THE STRUCTURE OF ALLYLIC GRIGNARD REAGENTS

Abstract

7‐Methyl‐, ‐äthyl‐, ‐isopropyl‐ und ‐tert.‐butylsubstituierte Allylgrignardverbindungen und ozq‐Dimethylallylmagnesiumchlorid werden NMR‐spektroskopisch untersucht.

Application of Allylzinc Reagents as Nucleophiles in Matteson Homologations

“…NMR studies by Grutzner et al indicated that (E)-and (Z)-crotylmagnesium halides are in a fast equilibrium even at −80 °C. 34 Analogous to the allylation reaction, the first examples with the "methylated" allyl Grignard reagents were conducted according to the one-pot protocol, when the αchloroboronic ester formed in the first step was directly reacted with the Grignard reagents (Scheme 2). 4a and 4a′ proved to be less reactive than unsubstituted AllylMgBr, and full conversion was reached only at room temperature.…”