ChemInform Abstract: Chiral‐at‐Metal Octahedral Iridium Catalyst for the Asymmetric Construction of an All‐Carbon Quaternary Stereocenter.

Abstract

Construction of an All-Carbon Quaternary Stereocenter.-An iridium complex that draws its chirality exclusively from an Ir-centered octahedral stereocenter is described as highly efficient catalyst for the asymmetric Michael addition of indoles to nitroacrylic esters to give products with quaternary stereocenters with excellent stereoselectivity. -(CHEN, L.-A.; TANG, X.; XI, J.; XU, W.; GONG, L.; MEGGERS*, E.; Angew.