ChemInform Abstract: Cesium Carbonate‐Promoted Hydroamidation of Alkynes: Enamides, Indoles and the Effect of Iron(III) Chloride.

Abstract

Cesium Carbonate-Promoted Hydroamidation of Alkynes: Enamides, Indoles and the Effect of Iron(III) Chloride. -A simple procedure for the title synthesis is developed by using a mild base. In some cases the addition of a catalytic amount of FeCl3·6H2O gives better yields. The unprotected indoles are obtained from the N-acylated anilides with exception of the compound (XVI). -(HERRERO, M. T.; DIAZ DE SARRALDE, J.; SANMARTIN, R.; BRAVO, L.; DOMINGUEZ*, E.; Adv. Synth. Catal. 354 (2012) 16, 3054-3064, http://dx.