ChemInform Abstract: Catalytic Oxidative Carbonylation of Arylamines to Ureas with W(CO)₆/I₂ as Catalyst.

Abstract

Title carbonylation reaction of a wide variety of aromatic amines (I) with carbon monoxide is smoothly achieved in the system iodine—DMAP—W(CO)6 to give symmetrical diarylurea derivatives (III).

Direct additive-free N-formylation and N-acylation of anilines and synthesis of urea derivatives using green, efficient, and reusable deep eutectic solvent ([ChCl][ZnCl2]2)

“…Several synthetic processes have been reported for the creation of urea structures 64 , 65 . Many transition metal-catalyzed processes including metals like Pd 66 , 67 , Mn 68 , W 69 , Au 70 , Ni 71 , and Ru 72 have been used to synthesize urea. Conventional approaches, such as the interaction of amines with commercially or in situ-produced isocyanates, continue to be one of the most straightforward and accessible ways to obtain these molecules 73 , 74 .…”