ChemInform Abstract: Catalytic Glycosylation with Glycosyl Thioimidate Donors.

Abstract

Carbohydrates U 0500Catalytic Glycosylation with Glycosyl Thioimidate Donors. -A new class of glycosyl thioimidates such as (III) or (VII) are easily prepared from readily available glycosyl thiols. These thioimidates can be activated effectively with catalytic amounts of a Lewis acid to give the glycosidation products. The availability, high stability, and catalytic activating properties of this type of donors may render them a great use in carbohydrate synthesis. -(LUCAS-LOPEZ, C.; MURPHY, N.; ZHU*, X.; Eur. J. Org. Chem. 2008, 26, 4401-4404; Cent. Synth. Chem. Biol., Univ. Coll., Belfield, Dublin, Ire.; Eng.) -Kieslich 02-196