ChemInform Abstract: Catalytic Enantioselective Quick Route to Aldol‐Tethered 1,6‐ and 1,7‐Enynes from ω‐Unsaturated Aldehydes.

Abstract

Catalytic Enantioselective Quick Route to Aldol-Tethered 1,6-and 1,7-Enynes from -Unsaturated Aldehydes. -Direct cross-aldol reaction between -unsaturated aldehydes and propargylic aldehydes is developed to yield functionalized 1,6-and 1,7-enynes and the conversion of these products to bicyclic cyclopentenone derivatives by Pauson-Khand reaction is demonstrated. -(GARCIA, J. M.; ODRIOZOLA, J. M.; RAZKIN, J.; LAPUERTA, I.; ODRIOZOLA, A.; URRUZUNO, I.; VERA, S.; OIARBIDE, M.; PALOMO*, C.; Chem. -Eur. J. 20 (2014) 47, 15543-15554, http://dx.