ChemInform Abstract: Biosynthesis of the Mould Metabolites Roquefortine (I) and Aszonalenin (II) from L‐(2,4,5,6,7‐2H5)Tryptophan

Abstract

Biosynthesis of the Mould Metabolites Roquefortine (I) and Aszonalenin (II) from L-(2,4,5,6,7-2H5)Tryptophan -(incorporation of labelled L-tryptophan into (I) by Penicillium roqueforti and (II) by Aspergillus zonatus with retention of five deuterium atoms; the 5a-hydrogen of (I) and (II) is derived from the 2-hydrogen of tryptophan). -(BHAT, B.; HARRISON, D. M.; LAMONT, H. M.; Tetrahedron 49 (1993) 46, 10663-10668; Dep. Chem., Univ. Warwick, Coventry CV4 7AL, UK; EN)