ChemInform Abstract: BIOLOGICALLY ACTIVE STABLE RADICALS; XV. SPIN‐LABELED ALKYL CARBAMATE‐N‐PHOSPHONIC ACID AZIRIDIDES

Жданов, Р. И.; Buina, N. A.; Kapitanova, N. G.; Нуретдинов, И. А.

doi:10.1002/chin.197931325

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2004

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“…The presence of nitrogen in these compounds promotes antitumour activity [1][2][3], whereas carbamate moieties are responsible for antitumour activity [4] as well as bactericidal activity [5,6]. These compounds also exhibit pesticidal activity [7].…”

Section: Introductionmentioning

confidence: 99%

QSAR studies of 2-substituted 2,3-dihydro-1h-naphtho[1,8-de]-1,3,2-diazaphosphorine 2-oxides and sulphides

et al. 2004

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A quantitative structure activity relationship (QSAR) study of 2-substituted 2,3-dihydro-1H-naphtho[1,8,de]-1,3,2-diazaphosphorine 2-oxides and sulphides (DND), examines the extent of the contribution by various physicochemical parameters with respect to their antimicrobial activity. Simple bivariant regression analysis, based on the least squares method, is applied in order to predict models. The predicted models reveal that the steric factor, MR, is the major contributor influencing antimicrobial activity. Bulky groups at the C-19 (C=O group) position positively influence the potency of the compounds.

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Section: Introductionmentioning

confidence: 99%

QSAR studies of 2-substituted 2,3-dihydro-1h-naphtho[1,8-de]-1,3,2-diazaphosphorine 2-oxides and sulphides

et al. 2004

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ChemInform Abstract: BIOLOGICALLY ACTIVE STABLE RADICALS; XV. SPIN‐LABELED ALKYL CARBAMATE‐N‐PHOSPHONIC ACID AZIRIDIDES

Abstract: Das Nitroxyl‐Derivat (II) wird an Dichlorphosphonylisocyanat (I) zum Carbamat (III) addiert, dessen Umsetzung mit Aziridinen (IV) die Aziridylphosphono‐nitroxyle (V) liefert.

Cited by 1 publication

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QSAR studies of 2-substituted 2,3-dihydro-1h-naphtho[1,8-de]-1,3,2-diazaphosphorine 2-oxides and sulphides

QSAR studies of 2-substituted 2,3-dihydro-1h-naphtho[1,8-de]-1,3,2-diazaphosphorine 2-oxides and sulphides

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