ChemInform Abstract: Asymmetric Michael/Cyclization Cascade Reaction of 3‐Isothiocyanato Oxindoles and 3‐Nitroindoles with Amino‐Thiocarbamate Catalysts: Enantioselective Synthesis of Polycyclic Spirooxindoles.

Abstract

The scalable and efficient method provides various polycyclic spirooxindoles with three contiguous chiral centers, two of which are quarternary, in excellent yields and with high to excellent dia‐ and enantioselectivities.