ChemInform Abstract: Aryl Esters and a Coumarin from Argyreia speciosa.

Srivastava, Anushree; Shukla, Y. N.

doi:10.1002/chin.199838267

Cited by 12 publications

(10 citation statements)

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“…It also displayed a positive response in the Lieberman–Burchard test. These results suggested that compound 1 possessed a basic triterpenoid skeleton [ 15 ]. The molecular formula of 1 was established as C 33 H 56 O 3 by the pseudomolecular [M+Na] + ion peak at m/z 523.4122 in HR-ESI-MS analysis and was further supported by its 13 C-NMR spectrum which showed signals for all 33 carbons of the molecule, including one set of terminal methylenes (δ C 111.9, 147.4), three oxygenated carbons (δ C 62.8, 71.0, 83.2), and seven methyl carbons (δ C 15.1, 18.1, 19.0, 19.3, 20.7, 21.3, 25.7).…”

Section: Resultsmentioning

confidence: 99%

Chemical Constituents from the Leaves of Annona reticulata and Their Inhibitory Effects on NO Production

et al. 2013

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In the present study, the chemical investigation of the leaves of Annona reticulata has resulted in the identification of nine compounds, including annonaretin A, (1), a new triterpenoid. The purified compounds were subjected to the examination of their effects on NO inhibition in LPS-activated mouse peritoneal macrophages and most of them exhibited significant NO inhibition, with IC50 values in the range of 48.6 ± 1.2 and 99.8 ± 0.4 μM.

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Section: Resultsmentioning

confidence: 99%

Chemical Constituents from the Leaves of Annona reticulata and Their Inhibitory Effects on NO Production

et al. 2013

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“…The plant has been screened for antiinflammatory (Gokhale et al, 2002), immunomodulatory (Gokhale et al, 2003), and hepatoprotective (Habbu et al, 2008), antimicrobial and antitubercular (Habbu et al, 2009) and nootropic (Habbu et al, 2009) activities. Phytochemical investigations on the roots of A. speciosa have resulted in the isolation of a range of biologically active substances like Flavonoid sulphates (Petra et al, 1999), Stigmasteryl p-hydroxycinnamate and a Coumarin (Srivastava and Shukla, 1998) and many phenolic compounds. We reported the isolation, characterization, antimicrobial antituberculosis efficacy of flavanoid suphates and other fractions of A. speciosa (Habbu et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

Antidiabetic activity of Argyreia speciosa (sweet) (Burm.f.)Boj. in normoglycemic and Streptozotocin-induced diabetic rats

Habbu¹,

Mahadevan²,

Kulkarni³

et al. 2010

Oriental Pharmacy and Experimental Medicine

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SUMMARYEffect of ethanol (ASE) and water (ASW) extracts of Argyreia speciosa on blood glucose and lipid profile was investigated in normoglycemic and Streptozotocin (STZ)-induced diabetic animals. In oral glucose and sucrose tolerance test, treatment with ASE and ASW (100 and 200 mg/kg) and Glidenclamide (10 mg/kg) significantly improved the glucose and sucrose tolerance in normal animals. In addition, respective treatment for fifteen-day resulted in significant percentage reduction in serum glucose (SG) ie., 30.39% (lower dose of ASE) and 33.21% (higher dose of ASW). In standardized STZ (50 mg/kg, iv)-induced diabetic rats, a single dose of ASE and ASW treatment exhibited reduction in SG levels at different time intervals compared to basal levels. Administration of both the doses of ASE and ASW for fifteen-day days exhibited greater percentage reduction in glycemia (24.6%, 24.7%, 23.9% and 21.9% respectively) and also ameliorated restored to near normal value of all tested lipid parameters. Further, treatment also exhibited significantly improved glucose tolerance over the period of 120 min compared to diabetic control group. Eventhough treatment failed to increase serum insulin levels significantly but peripheral utilization of insulin was increased as evident by insulin tolerance test. Taken together, present study supports the traditional usage of title plant in the treatment of diabetes mellitus.

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“…It also displayed positive responses against the Lieberman-Burchard test. These results suggested compound 1 to be a triterpenoid [50]. The molecular formula of 1 was established as C 32 H 52 O 5 by the pseudomolecular [M+H] + ion peak at m/z 517.3896 in HR-FAB-MS analysis and was further supported by its 13 C-NMR spectrum which showed signals for all the 32 carbons of the molecule including one set of acetyl group ( δ C 171.0, 21.3), one carboxylic acid group ( δ C 176.8), one oxygenated quaternary carbon ( δ C 90.1), and one acetoxygenated carbon ( δ C 80.9), respectively.…”

Section: Resultsmentioning

confidence: 99%

Chemical Constituents from the Fruits ofForsythia suspensaand Their Antimicrobial Activity

Kuo

Chen

Yang

et al. 2014

BioMed Research International

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Lignans and phenylethanoid glycosides purified from Forsythia suspensa were reported to display various bioactivities in the previous literature, including the antimicrobial activity. Therefore, the present research is aimed to purify and identify the chemical constituents of the methanol extracts of fruits of F. suspensa. The methanol extracts of fruits of F. suspensa were fractionated and further purified with the assistance of column chromatography to afford totally thirty-four compounds. Among these isolates, 3β-acetoxy-20α-hydroxyursan-28-oic acid (1) was reported from the natural sources for the first time. Some of the purified principles were subjected to the antimicrobial activity examinations against Escherichia coli to explore new natural lead compounds.

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ChemInform Abstract: Aryl Esters and a Coumarin from Argyreia speciosa.

Cited by 12 publications

References 0 publications

Chemical Constituents from the Leaves of Annona reticulata and Their Inhibitory Effects on NO Production

Chemical Constituents from the Leaves of Annona reticulata and Their Inhibitory Effects on NO Production

Antidiabetic activity of Argyreia speciosa (sweet) (Burm.f.)Boj. in normoglycemic and Streptozotocin-induced diabetic rats

Chemical Constituents from the Fruits ofForsythia suspensaand Their Antimicrobial Activity

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