ChemInform Abstract: Applications of Organosulfur Chemistry to Organic Synthesis: Total Synthesis of (+)‐Himbeline and (+)‐Himbacine.

Abstract

Applications of Organosulfur Chemistry to Organic Synthesis: Total Synthesis of (+)-Himbeline and (+)-Himbacine.-The total synthesis of himbeline (IXa) and himbacine (IXb) involves the preparation of sulfone (VI) and aldehyde (VII) as single enantiomers followed by coupling of these compounds using a Julia-Lythgoe olefination. -(HART, D. J.; LI, J.; WU, W.-L.; KOZIKOWSKI, A. P.; J. Org. Chem. 62 (1997) 15, 5023-5033; Dep. Chem., Ohio State Univ., Columbus, OH 43210, USA; EN)