ChemInform Abstract: Antifungal Steroidal Lactones from Withania coagulance.

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Withanolides and Related Steroids

“…The configurations at positions 24 and 25 of the latter compound were not elucidated. Also within this group are three withanolides with an additional sugar moiety at C-27 (21), withanosides VIII (35), IX (36), and X (37) (this structure was reported again as new, one year later (15)), an analogue of withanoside VI with a monosacharide at C-3 named withanoside XI (38) (21), and an analogue of withanoside IV with a trisacharide moiety at C-3 (39) (15 Glucosomniferanolide (57), isolated from W. somnifera, contains a glucose unit at the tertiary hydroxy group at C-20 (39). This compound was described as having a (22S) configuration, opposite to that found in all withanolides with a d-lactone side chain.…”

“…4.1.4.) showed antifungal activity against the human pathogens (MIC 300 mg/cm 3 ) Aspergillus niger, Stachybotrys atra, Allescheria boydii, Drechslera rostrata, Microsporum canis, and Curvularia lunata (36,43).…”

Proximate and nutrient analysis of selected medicinal plants of Tank and South Waziristan area of Pakistan

“…Traditionally, Alhagi maurorum is used for gastrointestinal disorders, gastric ulcer and rheumatism (Khushbaktovaet al, 1992). Withania coagulans is used for the treatment of diabetes mellitus (Abouzid et al, 2010) and have antibacterial, antifungal (Hemalatha et al, 2008), antiinflammatory (Choudhary et al, 1995), antitumor cardiovascular activity (Gaind et al, 1967;Khan et al, 1993). Berberis lyceum is well known for its anti-inflammatory and immune-potentiating property (Gupta et al, 2008).…”

Biological screening of Albizia lebbek L. and Mimosa himalayana Gamble (Mimosaceae)

“…Antibacterial activity was carried out by agar diffusion method and antifungal activity was carried out by using agar tube dilution as reported by Choudhary et al (1995). Micro organisms used in this study were Bacillus subtilis Ecscherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, Aspergillus niger and Aspergillus flavus.…”