Abstract:An Efficient Scale up Process for Synthesis of N-Arylpiperazines. -An efficient protocol for the synthesis of various substituted phenylpiperazines is presented using sulfolane as solvent. The procedure is clean, high yielding and products are obtained in high purities (>99%). It is also fast and convenient, as the final products are precipitated as the hydrochloride salts and can be isolated by filtration. -(RAVILLA, L.; SUBBA NAIDU, N. V.; NAGARAJAN*, K.; Tetrahedron Lett. 56 (2015) 30, 4541-4544, http://dx.
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