ChemInform Abstract: An Efficient Oxidative Dearomatization—Radical Cyclization Approach to Symmetrically Substituted Bicyclic Guttiferone Natural Products.

Abstract

The core structure (VI) of guttiferone terpenes such as (VII) is prepared via a diacetoxyiodobenzene--mediated oxidative dearomatization of phenol (II) and a subsequent radical cyclization of the resulting ketal as key steps. -(MCGRATH, N. A.; BINNER, J. R.; MARKOPOULOS, G.; BRICHACEK, M.; NJARDARSON*, J. T.; Chem. Commun. (Cambridge) 47 (2011) 1, 209-211, http://dx.