ChemInform Abstract: Acylation of Oxazolo[4,5‐b]pyridin‐2(3H)‐ones, 2‐Phenyloxazolo[4,5‐b]pyridines and Pyrrolo[2,3‐b]pyridin‐2(2H)‐ones.

Abstract

Acylation of Oxazolo [4,5-b]pyridin-2(3H)-ones, 2-Phenyloxazolo [4,5b]pyridines and Pyrrolo[2,3-b]pyridin-2(2H)-ones.-Several title compounds are acetylated and benzoylated using Pd-complexes as catalysts. The analgesic properties of the compounds are studied. Among these derivatives compound (X) possesses potent antinociceptive activity with moderate antiinflammatory properties. -(VIAUD, M.-C.; JAMONEAU, P.; BAUDIN, M.-L.; SAVELON, L.; GUILLAUMET, G.; Tetrahedron 53 (1997) 14, 5159-5168; Inst.