ChemInform Abstract: A Simple and General One‐Pot Synthesis of Some 2H‐Pyran‐2‐ones and Fused Pyran‐2‐ones.

Abstract

Dicarbonyl compounds such as (I) and (VII) react with N‐acylglycines such as (III) and (VI) and one‐carbon synthons such as (II) and (VIII) to yield pyranones (IV) and (V).

Diels–Alder reaction of fused pyran-2-ones with ethyl vinyl ether

“…Diels-Alder reactions between a set of fused pyran-2-ones 1 [35][36][37] and ethyl vinyl ether (2; see Scheme 1) were initially conducted in closed vessels (10 cm 3 ) under microwave irradiation [38][39][40][41][42][43][44][45][46] at 120°C, with the addition of DABCO as the catalyst. We found that such conditions (analogous to those used previously) [31,32] were not adequate to achieve quantitative conversion into the products 5; indeed, the only way to achieve this was to apply higher reaction temperatures (140-180°C).…”

“…1 H NMR spectra were recorded at 29°C with a Bruker (Rheinstetten, Germany) Avance DPX 300 spectrometer at 300 MHz or Bruker Avance III spectrometer at 500 MHz, using TMS as an internal standard. 13 [35][36][37]. All other reagents and solvents were used as received from commercial suppliers.…”

Reactions of 6-Acetyl-4-methyl-5-(1-pyrrolyl)-2-phenylthieno- [2,3-d]pyrimidine in Heterocyclic Synthesis: Convenient Route to Some Schiff's Bases, Chalcones, Pyridines, Pyridin-2(1H)-ones and 2H-Pyran-2-one Derivatives Incorporating a 5-(1-Pyrrolyl)-2-ph

“…[30][31][32] In conclusion, 6-acetyl-5-(1-pyrrolyl)-4-methyl-2-phenylthieno[2,3-d]pyrimidine 4 has been shown to be a useful building block for the synthesis of some new Schiff's bases 6a-f, chalcones 15a-k, pyridines 21a-f, pyridin-2(1H)-ones 26a,b and 2H-pyran-2-one derivatives 30a-c.…”

Synthesis and Crystal Structures of Methyl 3-(Benzoylamino)-6-methyl-2-oxo-2H-pyran-5-carboxylate and N-[5-(3,4-Dimethoxyphenyl)-6-methyl-2-oxo-2H-pyran-3-yl]benzamide

“…Due to the wide applicability of 2H-pyran-2-ones, a straightforward one-pot synthesis starting from the simple commercially available compounds was desired [19][20][21].…”