ChemInform Abstract: A Novel Method for the Synthesis of Diquinanes Based on Anionic [1,3] Rearrangement of Bicyclo[3.2.1]oct‐6‐en‐2‐ols.

Abstract

A Novel Method for the Synthesis of Diquinanes Based on Anionic [1,3] Rearrangement of Bicyclo[3.2.1]oct-6-en-2-ols.-A novel methodology for the construction of diquinanes (X) related to the sesquiterpene lactones ptychanolide or spirodensifolin A is described by employing a combination of pinacol-type rearrangement of the alcohol (V) and an efficient anionic [1,3] rearrangement of the bridged alcohol (VIII). -(HASHIMOTO,