ChemInform Abstract: A Highly Efficient Tandem Knoevenagel/Michael Reaction Using Mohr′s Salt Hexahydrate as a Green and Powerful Catalyst: Selective Synthesis of Benzylpyrazolocoumarins on Water.

Abstract

A Highly Efficient Tandem Knoevenagel/Michael Reaction Using Mohr's Salt Hexahydrate as a Green and Powerful Catalyst: Selective Synthesis of Benzylpyrazolocoumarins on Water. -(ESKANDARI*, K.; KARAMI, B.; KHODABAKHSHI, S.; FARAHI, M.; J. Chin. Chem. Soc. (Weinheim, Ger.) 62 (2015) 6, 473-478, http://dx.doi.org/10.1002/jccs.201400283 ; Dep. Chem., Yasouj Univ., Yasouj 75918, Iran; Eng.) -A. Forchert 43-154

Insights into 4,4′‐Arylmethylene‐Bis‐1H‐Pyrazol‐5‐Ols Scaffolds: Various Synthetic Routes and Their Applications

“…The high efficiency, operational simplicity, minimum reaction time, outstanding yields, high rate, and environmental safety are noticeable advantages of this procedure (Scheme 16). [67] Gupta et al established two efficient, very simple, and environmentally benign protocols for synthesis of (3) catalyst free, solid support, simply by microwave irradiation at 300 W or heating at 120 °C mixtures of (2) and aldehyde (1) in 2 : 1 mole ratio (Scheme 17). [68] Kumar et al have devised an effective, inexpensive, and environmentally sustainable amphiphile-catalyzed multicomponent reaction of (2) aromatic aldehydes (1) and secondary amines (10) in an aqueous medium catalyzed one-pot synthesis of (3) through a Knoevenagel-Michael type reaction(Scheme 18).…”

“…The high efficiency, operational simplicity, minimum reaction time, outstanding yields, high rate, and environmental safety are noticeable advantages of this procedure (Scheme 16). [67] Gupta et al . established two efficient, very simple, and environmentally benign protocols for synthesis of (3) catalyst free, solid support, simply by microwave irradiation at 300 W or heating at 120 °C mixtures of (2) and aldehyde (1) in 2 : 1 mole ratio (Scheme 17).…”