ChemInform Abstract: A Heteroaromatic Acid from Marine Sponge Suberites vestigium.

Abstract

A Heteroaromatic Acid from Marine Sponge Suberites vestigium.-Compound (I) is isolated from the butanol fraction of the marine sponge Suberites vestigium. It is the first time that a pyrazole derivative is isolated from marine flora and fauna. -(MISHRA, P. D.; WAHIDULLAH, S.; KAMAT, S. Y.; Indian J.

An experimental and theoretical approach to molecular structure of 4-benzoyl-5-phenyl-1-p-methoxyphenyl-1H-pyrazole-3-carboxylic acid methanol solvate

“…Pyrazoles are important compounds that have many derivatives with a wide range of interesting properties [1][2][3][4]. Recyclization reactions of 4-benzoyl-5-phenyl-2,3-dihydro-2,3-furandione with various phenylhydrazones and phenylhydrazine lead to pyrazolecarboxylic acid and pyridazinones [5,6].…”

Synthesis of some novel pyrazoline‐thiazole hybrids and their antimicrobial activities

“…Pyrazole, five‐member heterocyclic ring with two adjacent nitrogen atoms, has gained a great attention in pharmaceutical and chemical industries . A large number of pyrazoles showed various biological activities such as anticancer, antihistaminic, pesticidal, antifungal, anti‐rheumatoid arthritis, anticonvulsant, antidepressant, antipyretic, antibacterial, antituberculosis, antiviral, and anti‐inflammatory activities.…”

Water mediated self assembly of 5-(2-benzoimidazole-1-yl-ethoxy)-3-methyl-1-phenyl-1H-pyrazole-4-carboxylic acid methyl ester through CH⋯O and OH⋯N interactions

“…For example, water molecules at protein-DNA interface contribute to the complex formation and potentially play important role in mediating specific interactions [16][17][18]. The chemistry of pyrazole derivatives has been the subject of research due to their importance in various applications and their wide spread of potential biological and pharmacological activities governed by specific interactions between host and receptors [19][20][21][22][23][24][25][26][27][28][29][30][31][32][33]. In the present study, self assembly of compound (2) mediated through water molecules is reported which reveals an CAHÁ Á ÁO contact between 0022-2860/$ -see front matter Ó 2011 Elsevier B.V. All rights reserved.…”