ChemInform Abstract: A General Access to 1,1‐Cyclopropane Aminoketones and Their Conversion into 2‐Benzoyl Quinolines.

Abstract

A General Access to 1,1-Cyclopropane Aminoketones and Their Conversion into 2-Benzoyl Quinolines. -A novel, direct synthesis of 1,1-cyclopropane aminoketones via base-mediated tandem reaction of α-amino ketones with vinyl sulfonium salts is developed. These cyclopropane aminoketones can be easily transformed into 2-benzoylquinolines via treatment with DEAD. -(MAO, Z.; QU, H.; ZHAO, Y.; LIN*, X.; Chem. Commun. (Cambridge) 48 (2012) 79, 9927-9929, http://dx.