ChemInform Abstract: A Facile Stereocontrolled Synthesis of anti‐α‐(Trifluoromethyl)‐β‐amino Alcohols.

Abstract

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Synthesis of enantiopure 2‐(aminoalkyl)phenol derivatives and their application as catalysts in stereoselective reactions

“…[42][43][44][45][46][47][48][49] It is interesting that the synthesis of variously functionalized 2-(aminoalkyl)phenols through the condensation of alkenyl, aryl, or heteroaryl boronic acids with amines and salicylaldehydes. 50 The final 2-(aminoalkyl)-phenol 12 is obtained through an intramolecular addition (Scheme 7).…”