Abstract:Rearrangements O 0140 A Convenient Synthesis of Sulfonylureas from Carboxylic Acids and Sulfonamides via an in situ CurtiusRearrangement. -Condensation of sulfonamides with carboxylic acids, promoted by diphenylphosphoryl azide, allows the synthesis of sulfonyl ureas. An example for the formation of an acyl urea [cf. product (VIII)] is also given. -(LUCKHURST*, C. A.; MILLICHIP, I.; PARKER, B.; REUBERSON, J.; FURBER, M.; Tetrahedron Lett. 48 (2007) 50, 8878-8882; Dep. Med. Chem., AstraZeneca R&D Charnwood, Lou… Show more
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