ChemInform Abstract: 3‐Acyl‐1,5‐benzodiazepines in the Reactions of 5,5‐Dimethyl‐2‐formylcyclohexane‐1,3‐dione with Certain 1,2‐Diaminobenzenes.

Abstract

3-Acyl-1,5-benzodiazepines in the Reactions of 5,5-Dimethyl-2formylcyclohexane-1,3-dione with Certain 1,2-Diaminobenzenes. -Reaction of 2-formylcyclohexanedione (I) with substituted 1,2-diaminobenzenes (II) gives the corresponding enamines (III) or (IV) which cyclize on treatment with conc. HCl to furnish dibenzodiazepine derivatives (V) or (VI), respectively. Hydrolysis results in reformation of starting enamine or cleavage of the C 11 -N 10 bond [→(VIII)]. -(GURKOVSKII, A. I.; TONKIKH, N. N.; PETROVA, M. V.; STRAKOV, A. YA.; Chem. Heterocycl.