ChemInform Abstract: 1H‐1,2,4‐Triazole Angiotensin II Receptor Antagonists: “C‐Linked” Analogues of SC‐50560.

Abstract

1H-1,2,4-Triazole Angiotensin II Receptor Antagonists: "C-Linked" Analogues of SC-50560.-Biaryl (VI) shows nearly identical pharmacological effects in rats as its known N-linked analogue. -(REITZ, D. B.; PENICK, M. A.; NORTON, M. B.; REINHARD, E. J.; OLINS, G. M.; CORPUS, V. M.; PALOMO, M. A.; MCGRAW, D. E.; MCMAHON, E. G.; Bioorg. Med. Chem. Lett. 4 (1994) 1, 105-110; Searle Res. Dev., Monsanto Co., St. Louis, MO 63198, USA; EN)