Abstract:The 13C chemical shifts for 1,3-dioxaneand 50 methyl-substituted derivatives are reported. Substituent effectson them are derived and their magnitude shown to be closelyrelated to the exact ring geometry and other conformational aspects. The results confirm the high chair-twist preference and support the view that 1,4-twist is appreciably more stable than 2,5-twist. Only 2,4-diaxially substituted compounds normally attain a twist form whereas 4,6-diaxial substitution alone is not enough but deform the chair fo… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.