Chemiluminescence sensing of adenosine using DNA cross-linked hydrogel-capped magnetic mesoporous silica nanoparticles

Hou, Yanan; Han, Rui; Sun, Yuanling; Luo, Chuannan

doi:10.1016/j.aca.2021.339386

Cited by 17 publications

(9 citation statements)

References 46 publications

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“…In chemical reaction method, the functional groups in the molecular chain of a polymer react with each other to form covalent bonds; examples include the thiololefn click reaction [ 100 ], Schiff base reaction [ 78 ], free-radical polymerization [ 101 ], and hybridization chain reaction [ 31 ]. A gel formed by chemical crosslinking has higher mechanical properties and no melting or dissolving.…”

Section: Crosslinking Methods Of Mesoporous Material-loaded Composite...mentioning

confidence: 99%

Mesoporous Materials Make Hydrogels More Powerful in Biomedicine

Chen

Qiu

Xia

et al. 2023

Gels

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Scientists have been attempting to improve the properties of mesoporous materials and expand their application since the 1990s, and the combination with hydrogels, macromolecular biological materials, is one of the research focuses currently. Uniform mesoporous structure, high specific surface area, good biocompatibility, and biodegradability make the combined use of mesoporous materials more suitable for the sustained release of loaded drugs than single hydrogels. As a joint result, they can achieve tumor targeting, tumor environment stimulation responsiveness, and multiple therapeutic platforms such as photothermal therapy and photodynamic therapy. Due to the photothermal conversion ability, mesoporous materials can significantly improve the antibacterial ability of hydrogels and offer a novel photocatalytic antibacterial mode. In bone repair systems, mesoporous materials remarkably strengthen the mineralization and mechanical properties of hydrogels, aside from being used as drug carriers to load and release various bioactivators to promote osteogenesis. In hemostasis, mesoporous materials greatly elevate the water absorption rate of hydrogels, enhance the mechanical strength of the blood clot, and dramatically shorten the bleeding time. As for wound healing and tissue regeneration, incorporating mesoporous materials can be promising for enhancing vessel formation and cell proliferation of hydrogels. In this paper, we introduce the classification and preparation methods of mesoporous material-loaded composite hydrogels and highlight the applications of composite hydrogels in drug delivery, tumor therapy, antibacterial treatment, osteogenesis, hemostasis, and wound healing. We also summarize the latest research progress and point out future research directions. After searching, no research reporting these contents was found.

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Section: Crosslinking Methods Of Mesoporous Material-loaded Composite...mentioning

confidence: 99%

Mesoporous Materials Make Hydrogels More Powerful in Biomedicine

Chen

Qiu

Xia

et al. 2023

Gels

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“…DNA hydrogels have widely been used in recent years for constructing electrochemical biosensors because of their huge loading ability and satisfactory biocompatibility that can provide signal probes and amplification strategies. 10,11 Typically, there are two types of DNA hydrogels: pure DNA hydrogels and hybrid DNA hydrogels used in biosensor construction. 12 Their use as biosensors is limited due to slow mass transfer of large molecules that block rapid detection, 13 and because complex strategies are used in building DNA hydrogel biosensors.…”

Section: Introductionmentioning

confidence: 99%

“…There are numerous methods for building signal probes, such as chemical modification, 14 physical assemblies, 15 and loading cages. 11 It was found that nucleotides can form hydrogels with the assistance of small molecules and ions. The construction of nucleotide hydrogels is simple, and they possess a wide variety of abilities.…”

Section: Introductionmentioning

confidence: 99%

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Cytidine-rich hydrogel as an electrochemical signal amplification strategy for microRNA detection

Zhang

Yang

et al. 2022

Analyst

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“…Chemiluminescence (CL) is a chemical reaction that results in light being emitted. It is a high-authority analytical tool for detecting and quantifying various biological materials, such as cells, 7 microorganisms, proteins, 8 DNA, 9 RNA, and other analytes. 10 Because the luminescent fluorescence method, unlike other fluorescence detection methods, does not require light excitation, spontaneous fluorescence does not generate a background signal.…”

Section: Introductionmentioning

confidence: 99%