Chemiluminescence Resonance Energy Transfer Efficiency and Donor–Acceptor Distance: from Qualitative to Quantitative

Abstract

Since its birth in 1967, the utilization of chemiluminescence resonance energy transfer (CRET) has made substantial progress in av ariety of fields for its unique features. However,t he quantitative relationship between CRET efficiency and donor-acceptor distance has not yet been determined owing to the difficulty in designing the variable lengths between chemiluminescent donors and acceptors.H erein, we synthesized three kinds of tetraphenylethene (TPE)-anchored cationic surfactants with aggregation-induced emission (AIE) characteristics.F or the first time,i ti sq uantitatively demonstrated that the CRET efficiency is inversely proportional to the sixth power of distance between luminol donors and TPE acceptors.T he details disclosed in this contribute have provided the solid evidence that CRET follows Fçrster resonance theory.O ur strategy would build ap romising platform to control donor-acceptor distance,a llowing to the interdisciplinary applications of CRET.

Determination of the critical micelle concentration of surfactants using fluorescence strategies

“…[1][2][3] Surfactants in water or water-like media can easily form spherical micelles in which the hydrophilic headgroups are oriented toward water, and the hydrophobic moieties coalesce through non-covalent forces such as hydrophobic interaction. 3 The formed micelles have the innate ability to interact with both polar and nonpolar compounds, making them surprisingly advantageous and suitable for broad applications in decontamination, [4][5][6] template synthesis, [7][8][9] catalysis, [10][11][12] drug delivery, [13][14][15] analytical assays, [16][17][18] etc. The critical micelle concentration (CMC) is a key parameter that must be measured for surfactants, which indicates the minimum concentration required for micelle formation.…”

Chemiluminescence resonance energy transfer as a simple and sensitive readout mode for a CRISPR/Cas12a-based biosensing platform

“…The activated Cas12a can cleave effectively the Taqman probe (5′-BHQ-TTATT-FAM-3′), resulting in FAM (donor) away from BHQ (quencher). Because CRET efficiency is inversely proportional to the sixth power of distance between donors and acceptors, 29 the CRET between FAM and BHQ cannot occur. So, the addition of TCPO-H 2 O 2 into the system containing FAM will produce a strong CL emission.…”

Structure–property relationship study of blue thermally activated delayed fluorescence molecules with different donor and position substitutions: theoretical perspective and molecular design

“…61 Following the reported result by Lu, the chemiluminescence resonance energy transfer efficiency is inversely proportional to the sixth power of the donor-acceptor distance, which is consistent with Fo ¨rster's resonance theory. 62 The twist angle and rotation motion between the donor and acceptor in D-A typed molecules play an important role in the photophysical properties of such molecules. 63 Based on optimized structure (S 0 ), the bond length and dihedral angle between D-A typed groups are obtained and shown in Table 2.…”